A recent review of studies on gut dysbiosis and rheumatoid arthritis explored how the gut microbiome affects the disease. Imbalanced gut bacteria has been linked to increased inflammation, a key characteristic of rheumatoid arthritis. While there is no cure for the autoimmune disorder, researchers are looking into treatments and preventative options. Many experts are interested in how the gut microbiome can impact autoimmune disorders. Since specific bacteria in the gut can cause inflammation, researchers want to understand their role in conditions like rheumatoid arthritis.
Rheumatoid arthritis is a progressive disease that can cause joint pain, bone deformities, and affect multiple body systems like the eyes, lungs, and heart. While the exact cause of the disease is unclear, genetics and environmental factors may play a role. Some scientists believe that the gut microbiome could contribute to the development or worsening of rheumatoid arthritis symptoms. Trillions of microbes in the gut, including both good and bad bacteria, play a role in various bodily processes, and imbalances can disrupt the regulation of the immune system.
Certain bacteria in the gut have been associated with inflammatory molecules that may lead to inflammation in different body tissues, including joints. One bacterium, Prevotella copri, has been linked to the pathogenesis of rheumatoid arthritis. Studies in the review show that elevated P. copri can contribute to immune system dysfunction and joint damage. The review also indicates that diets high in fiber, carbohydrates, and simple sugars can lead to increased levels of P. copri, while other bacteria like Lactobacillus casei can have beneficial effects, such as lower levels of inflammation.
The foods and drinks people consume influence the gut microbiome, inflammation, and the body’s immune response, which can indirectly impact rheumatoid arthritis progression. Fiber is a crucial component in adjusting the gut microbiome and improving health outcomes for individuals with rheumatoid arthritis. Short-chain fatty acids produced by gut bacteria from fiber can enhance the intestinal barrier’s functioning and regulate the immune response. Dietary recommendations suggest that increased fiber intake can reduce symptoms of rheumatoid arthritis, and the Mediterranean diet, rich in whole grains, healthy fats, fruits, fish, and vegetables, can provide benefits for joint pain and inflammation.
Experts suggest that imbalances in the gut microbiome may contribute to rheumatoid arthritis, as people with the condition often have less diversity in their gut bacteria. While changes in the microbiome can lead to chronic inflammation, more research is needed to confirm the relationship between gut dysbiosis and rheumatoid arthritis. Steps individuals can take to improve gut health and reduce the risk of developing rheumatoid arthritis include consuming more fiber, omega-3 fatty acids from fish, and probiotic-rich foods. Consulting with a healthcare professional before making significant dietary or lifestyle changes is recommended for individuals looking to address gut dysbiosis through dietary interventions for rheumatoid arthritis.
